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Results of the Women's Health Initiative

Disease Estrogen + Progesterone Estrogen Alone Comments
Heart Disease Neither beneficial nor harmful Neither beneficial nor harmful Estrogen showed a 5% decrease in risk of heart disease, but this result was not statistically significant
Stroke 31% increased risk 39% increased risk
Blood Clots 100% increased risk 47% increased risk
Urinary Incontinence Increased risk Increased risk This result was a big surprise, because heretofore physicians have been prescribing hormones to help women with urinary incontinence.
Breast Cancer 24% increased risk No effect It was a surprise to find out that estrogen alone does not increase the risk of breast cancer.
Colon Cancer 44% decreased risk No effect Estrogen + Progesterone is now the only known intervention proven to decrease the risk of colon cancer.
Dementia 100% increased risk 49% increased risk This was a surprise, as it was previously believed that estrogen decreased the risk of dementia.
Hip Fractures 33% decreased risk 33% decreased risk One clear benefit of estrogen is reduced risk of fractures.
Diabetes 21% improvement 12% improvement These are improvements in insulin and glucose levels in patients who already have diabetes and are on hormones.
Gallbladder Disease 60% increased risk 60% increased risk